Every year, there are roughly 8 million bone fractures in United States [1]. In addition, approximately 2300 new cases of primary bone cancer are diagnosed each year [2]. Yet, the number of people suffering from bone disease is significantly greater; about 10 million people in the U.S. alone suffer from osteoporosis [3]. Consequently, surgeons perform nearly 500,000 bone graft operations annually making bone grafts the second most frequently transplanted materials [4]. Although there is an extremely high demand for treatment of bone abnormalities, the current grafting methods fail to meet these demands due to several limitations. Autografting has the fewest problems with rejection and pathogen transmission, however in some cases the availability may be limited or not be possible (e.g., genetic diseases). With other methods of transplantation such as allogafting and xenografting where tissue is acquired from other humans or species, respectively, the receptor’s immune system causes an increased risk of chronic rejection [5]. Notably, the major drawback with all these methods is that they often require multiple painful and invasive surgeries.
Skip Nav Destination
ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
February 7–10, 2010
Houston, Texas, USA
Conference Sponsors:
- ASME Nanotechnology Council
ISBN:
978-0-7918-4392-5
PROCEEDINGS PAPER
Electrospun Polycaprolactone-Nanodiamond Composite Scaffolds for Bone Tissue Engineering
Amanee D. Salaam,
Amanee D. Salaam
University of Alabama at Birmingham, Birmingham, AL
Search for other works by this author on:
Derrick Dean
Derrick Dean
University of Alabama at Birmingham, Birmingham, AL
Search for other works by this author on:
Amanee D. Salaam
University of Alabama at Birmingham, Birmingham, AL
Derrick Dean
University of Alabama at Birmingham, Birmingham, AL
Paper No:
NEMB2010-13298, pp. 367-370; 4 pages
Published Online:
December 22, 2010
Citation
Salaam, AD, & Dean, D. "Electrospun Polycaprolactone-Nanodiamond Composite Scaffolds for Bone Tissue Engineering." Proceedings of the ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. Houston, Texas, USA. February 7–10, 2010. pp. 367-370. ASME. https://doi.org/10.1115/NEMB2010-13298
Download citation file:
8
Views
Related Proceedings Papers
Related Articles
PMMA Implants Increase Femoral Strength
J. Med. Devices (June,2008)
Novel Natural Transdermal Otoliths/Collagen/Bacterial Cellulose Patch for Osteoporosis Treatment
J. Nanotechnol. Eng. Med (August,2011)
Low-Frequency Acoustic Sweep Monitoring of Bone Integrity and Osteoporosis
J Biomech Eng (August,1999)
Related Chapters
Experimental Studies
Nanoparticles and Brain Tumor Treatment
Conclusion & executive summary
Photodynamic Therapy Mediated by Fullerenes and their Derivatives
Introduction
Nanoparticles and Brain Tumor Treatment