Nanomedicine dosages are selected in part based on the competing goals of maximizing death of malignant cells while minimizing damage to healthy cells. Determination of proper nanomedicine dosage and concentration is difficult to due the lack of understanding of nanoparticle targeted delivery process in complex vascular environment. This paper presents a continuum model of the transportation and targeted deposition of nanoparticles in a vascular network, which is an essential component of a multi-scale targeted delivery predictive tool being developed.

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