The conformational dynamics and mechanical properties of supramolecular protein assemblies play a central role in a broad array of cellular functions ranging from migration and division to transcription and translation. The finite element method (FEM) provides a natural framework for the computation of protein normal modes and mechanical response based either on atomic coordinates or electron density maps [1]. Here, we present development of the finite element framework for the computation of actin filament mechanics and solvent damping effects. A new normal modes data bank for structures in the electron microscopy data bank (EMDB [2]) is also presented.

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