Magnetic microcapsules are often used as vesicles in targeted drug delivery systems, where focused magnetic field propels the capsules to highly specific locations in tissue. To fully realize this potential it is important to understand the dynamics of magnetically-responsive micrometer sized particles in viscous fluids and the effect of boundaries on particle motion. Furthermore, for practical biomedical applications, it could be useful to create synthetic micrometer-sized vesicles able to perform controlled self-propelled motion. Herein, using computer simulations, we examine the motion of magnetically-responsive synthetic microcapsules that able to crawl along walls in microchannels filled with a viscous fluid. The compliant fluid-filled capsules considered in this study encompass superparamagnetic nanoparticles in their solid shells and, therefore, can be manipulated by alternating magnetic forces.
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ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
February 7–10, 2010
Houston, Texas, USA
Conference Sponsors:
- ASME Nanotechnology Council
ISBN:
978-0-7918-4392-5
PROCEEDINGS PAPER
Regulating Motion of Magnetic Capsules in Microfluidic Systems Available to Purchase
Hassan Masoud,
Hassan Masoud
Georgia Institute of Technology, Atlanta, GA
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Alexander Kilimnik,
Alexander Kilimnik
Georgia Institute of Technology, Atlanta, GA
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Alexander Alexeev
Alexander Alexeev
Georgia Institute of Technology, Atlanta, GA
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Hassan Masoud
Georgia Institute of Technology, Atlanta, GA
Alexander Kilimnik
Georgia Institute of Technology, Atlanta, GA
Alexander Alexeev
Georgia Institute of Technology, Atlanta, GA
Paper No:
NEMB2010-13244, pp. 305-306; 2 pages
Published Online:
December 22, 2010
Citation
Masoud, H, Kilimnik, A, & Alexeev, A. "Regulating Motion of Magnetic Capsules in Microfluidic Systems." Proceedings of the ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. Houston, Texas, USA. February 7–10, 2010. pp. 305-306. ASME. https://doi.org/10.1115/NEMB2010-13244
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