A Self-Contained Microfluidic Cassette for the Detection of Nucleic Acids at the Point-of-Care

In recent years, there has been a growing interest in developing integrated, self-contained, disposable, inexpensive microfluidic devices for point-of-care diagnostics [1–3]. These devices are required to identify pathogens rapidly, facilitate use by minimally trained personnel, and be able to operate in regions where sophisticated laboratories are lacking.