Bioceramics with porous microstructure has attracted intense attention in tissue engineering due to tissue growth facilitation in the human body. In the present work, a novel manufacturing process for producing hydroxyapatite (HA) aerogels with a high density shell inspired by human bone microstructure is proposed for bone tissue engineering applications. This method combines laser processing and traditional freeze casting in which HA aerogel is prepared by freeze casting and aqueous suspension prior to laser processing of the aerogel surface with a focused CO2 laser beam that forms a dense layer on top of the porous microstructure. Using the proposed method, HA aerogel with dense shell was successfully prepared with a microstructure similar to human bone. The effect of laser process parameters on surface and cross-sectional morphology and microstructure was investigated in order to obtain optimum parameters and have a better understanding of the process. Low laser energy resulted in fragile surface with defects and cracks due to low temperature and inability of laser to fully melt the surface while high laser energy caused thermal damage both to surface and microstructure. The range of 40–45 W laser power, 5 mm/s scanning speed, spot size of 1 mmm and 50 % overlap in laser scanning the surface yielded the best surface morphology and micro structure in our experiments.
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ASME 2017 12th International Manufacturing Science and Engineering Conference collocated with the JSME/ASME 2017 6th International Conference on Materials and Processing
June 4–8, 2017
Los Angeles, California, USA
Conference Sponsors:
- Manufacturing Engineering Division
ISBN:
978-0-7918-5072-5
PROCEEDINGS PAPER
Laser Surface Engineering of Hierarchy Hydroxyapatite Aerogel for Bone Tissue Engineering
Pedram Parandoush
,
Pedram Parandoush
Kansas State University, Manhattan, KS
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Hanxiong Fan
,
Hanxiong Fan
Kansas State University, Manhattan, KS
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Xiaolei Song
,
Xiaolei Song
Kansas State University, Manhattan, KS
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Dong Lin
Dong Lin
Kansas State University, Manhattan, KS
Search for other works by this author on:
Pedram Parandoush
Kansas State University, Manhattan, KS
Hanxiong Fan
Kansas State University, Manhattan, KS
Xiaolei Song
Kansas State University, Manhattan, KS
Dong Lin
Kansas State University, Manhattan, KS
Paper No:
MSEC2017-3035, V001T02A050; 7 pages
Published Online:
July 24, 2017
Citation
Parandoush, P, Fan, H, Song, X, & Lin, D. "Laser Surface Engineering of Hierarchy Hydroxyapatite Aerogel for Bone Tissue Engineering." Proceedings of the ASME 2017 12th International Manufacturing Science and Engineering Conference collocated with the JSME/ASME 2017 6th International Conference on Materials and Processing. Volume 1: Processes. Los Angeles, California, USA. June 4–8, 2017. V001T02A050. ASME. https://doi.org/10.1115/MSEC2017-3035
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