Advancements in the field of microfluidics has led to an increasing interest to study laminar flow in microchannel and its potential applications. Understanding mixing at a microscale can be useful in various biological, heating and industrial applications due to the space and time reduction that micro mixing permits. This work aims to study mixing enhancement due to curved microchannel and the influence of varying microchannel cross sectional shape through numerical and experimental investigations. Unlike prior studies which use channel dimensions in the lower microscale range, this work has been conducted on channels with dimensions in the higher end of micrometer range. Using a cross sectional hydraulic diameter of 600 μm enables introduction of flow into the curved channel at a Reynolds Number ranging from 0.15 to 75, the findings of which show considerable improvement in the mixing performance as compared to that of equivalent straight channels, due to the development of secondary flows known as Dean Vortices.