To detect and identify biomolecules at its infectious dose, all sensors require a relatively long time — days or even weeks — for reliable results. This delay occurs because the collection of analyte molecules onto the sensing elements depends solely on the diffusion process of those agents to a sensor. This work seeks to enhance the transport process, and thereby significantly improve a sensor’s detection capability. This work investigates an in-situ, label-free nanoparticle (e.g. protein) preconcentrator based on a new AC electrothermal effect (ACET) that can operate even in a highly conductive solution for which current methods such as dielectrophoresis, electrophresis or electroosmosis won’t function effectively. The proposed AC electrokinetic preconcentrator is expected to significantly increase the nanoparticle counts, realizing sub-femto molar detection in real time.
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ASME 2009 Second International Conference on Micro/Nanoscale Heat and Mass Transfer
December 18–21, 2009
Shanghai, China
Conference Sponsors:
- Nanotechnology Institute
ISBN:
978-0-7918-4389-5
PROCEEDINGS PAPER
In Situ Electrokinetic Preconcentrator for Conductive Biofluids
Kai Yang
The University of Tennessee, Knoxville, TN
Jie Wu
The University of Tennessee, Knoxville, TN
Paper No:
MNHMT2009-18466, pp. 651-657; 7 pages
Published Online:
October 26, 2010
Citation
Yang, K, & Wu, J. "In Situ Electrokinetic Preconcentrator for Conductive Biofluids." Proceedings of the ASME 2009 Second International Conference on Micro/Nanoscale Heat and Mass Transfer. ASME 2009 Second International Conference on Micro/Nanoscale Heat and Mass Transfer, Volume 1. Shanghai, China. December 18–21, 2009. pp. 651-657. ASME. https://doi.org/10.1115/MNHMT2009-18466
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