The self-assembly of supramolecular complexes between DNA and lipophilic vitamins, e.g. vitamin D group was examined, in the absence and presence of different cations, to the first time. A novel method for preparing DNA-lipophilic vitamins nanostructured complexes in the existence of divalent cations is introduced. The nanostructure of the supramolecular complexes ranged from beads-on-strings to compact globules and liquid crystalline forms depending on the vitamin nature, cations concentration and incubation time. A nucleation mechanism and flower-like aggregates are proposed as an initial state for complex formation. The biomedical applications of the functional nanostructured supramolecular complexes will be discussed in details.
- Nanotechnology Institute
DNA-Lipophilic Vitamins Supramolecular Complexes
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Elkady, AS. "DNA-Lipophilic Vitamins Supramolecular Complexes." Proceedings of the ASME 2008 2nd Multifunctional Nanocomposites and Nanomaterials International Conference. ASME 2008 2nd Multifunctional Nanocomposites and Nanomaterials. Sharm El Sheikh, Egypt. January 11–13, 2008. pp. 213-216. ASME. https://doi.org/10.1115/MN2008-47031
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