Electronic cooling represents a major portion of a Data Centers energy consumption, thus efficient thermal management dramatically impacts energy savings. This work proposes reducing the energy consumption associated with server air-cooling by vectoring (tilting) the main upward tile flow using adjacent synthetic jets. The particular fluid dynamics generated by synthetic jets allows controlling the angle at which the tile flow emanates, directing the cooling air toward areas with higher cooling demand. Three-dimensional simulations were performed using k–ε standard turbulence model with the commercial software Ansys Fluent. In order to quantify and localize the inefficiencies of the system, we estimated the Exergy Destruction distribution in the cold aisle and servers. In previous studies, this technique proved successful in finding optimum operation conditions in Data Center cooling. As opposed to a base case without flow control, the adjacent synthetic jets directed the incoming fluid to areas with higher cooling demand, thus saving energy by avoiding over-provisioning air into servers operating under normal demand. The decrease in the overall Exergy Destruction demonstrated that vectoring improves the system’s global energy efficiency.