Catheter acquired urinary tract infection (CAUTI) is a significant problem in the medical community. Interdisciplinary teams have coordinated to address this problem, yet there is still a need for an adequate solution. In this study, we investigate an electricidal solution by adopting electrochemically active materials that can be incorporated into a urinary catheter. Zinc and silver oxide powders deposited in the form of patterned electrodes on a thermoplastic substrate are shown to illustrate electricidal properties in urine, including the ability to produce electric fields, pH increases, as well as, formation of hydrogen peroxide. The newly developed samples show promising results for killing planktonic E. coli in a controlled setting.