The Laboratory Air Handling Unit (LAHU) system is developed to improve building energy performance and indoor air quality (IAQ) in laboratory buildings. The LAHU system sends more (up to 100%) outside air to the office section first and re-circulates the office section air to the laboratory section. The theoretical model analysis shows that the LAHU system improves office section indoor air quality, uses less outside air during hot and cold weathers, and consumes significantly less thermal energy. The optimal control of outside air intake to office section maximizes IAQ improvement and thermal energy savings.

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