Rolling of the cell under flow conditions is an important process in PMN emigration. It is a finely regulated process involving membrane receptors and cell-matrix recognition. Several models have been proposed to explain how the strength and lifetime of the bonds in receptor-mediated cell-substratum are related to cell rolling velocity (Hammer, 1992, Tozeren, 1992, Zhao, 1995). The paper presents a simple model of the cell rolling based on the experimental measurements that will allow to gain information relevant to the molecular processes underlying the rolling motion of the cell.

This content is only available via PDF.
You do not currently have access to this content.