The current study investigates the effect of wind catcher-greenhouse integration on the micro-climatic conditions inside the green house. The potential application of wind tower in greenhouse systems for hot climatic conditions with water mist injection was carefully evaluated. The effect of various parameters such as air flow velocity, relative humidity, injector mass flow rate and injector position in the wind tower was studied. The variations in the temperature and relative humidity was observed in the greenhouse. The computational fluid dynamic analysis was carried out using Fluent and k-ε turbulence model was adopted for the analysis. A non-isothermal, multiple species, viscous and turbulent flow is pursued. It was observed that the addition of water injectors inside the wind catcher significantly reduced the temperature and enhanced the relative humidity of the air.