The aim of this study was to develop a test method to characterize the material behavior of bovine brain samples in large shear deformations and high strain rates relevant to blast-induced neurotrauma (BINT) and evaluate tissue damage. A novel shear test setup was designed and built capable of applying strain rates ranging from 300 to 1000 s−1. Based on the shear force time history and propagation of shear waves, it was found that the instantaneous shear modulus (about 6 kPa) was more than 3 times higher than the values previously reported in the literature. The shear wave velocity was found to be strain path dependent which is an indication of tissue damage at strains greater than 10%. The results of this study can help in improving finite element models of the brain for simulating tissue injury during BINT.

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