Traumatic brain injury (TBI) is one of the most common injuries to service members in recent conflicts. Computational models can offer insights in understanding the underlying mechanism of brain injury, which lead to the crucial development of effective personal protective equipment designed to prevent or mitigate the TBI.

Historically many computational models were developed for the brain injury study. However, these models use relatively coarse mesh with a less detailed head anatomy. Many models consider the head only and thus cannot properly model the real scenario, i.e., accidental fall, blunt impact or blast loading. A whole-body finite element model can represent the real scenario but is very expensive to use.

By combining the high-fidelity human head model with an articulated human body model, we developed the computational multi-fidelity human models to investigate the blunt- and blast-related TBI efficiently. A high-fidelity computational head model was generated from the high resolution image data to accurately reproduce the complex musculoskeletal and tissue structure of the head. The fast-running articulated human body model is based on the multi-body dynamics and was used to reconstruct the accidental falls. By utilizing the kinematics and force and moment at the joint of the articulated human body model, we can realistically simulate the blunt impact and assess the brain injury using the high-fidelity head model.

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