A two-dimensional ultrasonic-measurement-integrated (2D-UMI) blood flow analysis system was developed for easy acquisition of an intravascular hemodynamics, which feeds back Doppler velocity obtained by an ultrasonic measurement to a numerical blood flow simulation for clinical application. In previous study, ultrasonic measurement and 2D-UMI simulation were performed to clarify the analysis accuracy for real flow field. Additionally, spatial variation characteristics of analysis accuracy was clarified by comparison of velocity vectors between 2D-UMI and 3D-CFD analysis results corresponding to an experimental flow. However, temporal variation of analysis accuracy of 2D-UMI analysis result has not been examined in spite of essential information for reduction of experimental measurement error due to speckle noise.

The aim of this study was to clarify temporal variation characteristics of analysis accuracy of each velocity component obtained in 2D-UMI blood flow analysis. Comparisons of Doppler velocity V and (u, v) velocity profiles between measurement data, 2D-UMI, and 3D-CFD analysis results were performed, and their time variations were discussed. As a result, it was clarified that temporal variation of Doppler velocity error for measurement data became larger with increasing feedback gain. Temporal variations of u and v velocity component errors for 3D-CFD analysis result showed the same tendency as that of Doppler velocity in feedback gain.

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