During the maturation the high pressure blood from the artery inflows directly to the vein, extends its diameter, and finally the blood flow rate in the vein is even 500-times greater than normal one. The changes of the wall shear stress (WSS) in the vein are thought to play a key role in the remodelling of its wall. However, this process is still not well understood. The aim of this paper is to show an innovative approach for modelling of the vein deformation during the maturation process of a-v fistulas. Dilation of the vein was modelled as two-step complex biomechanical process.

The obtained results concerning final diameter of the vein are compared with average diameter obtained for large group of patients. Moreover, this study shows the changes in the flow rate and the WSS that occur after maturation in the patient-specific fistula.

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