Reliability based design and optimization approach is developed for femoral locking plate systems. The new approach encompasses finite element analysis, advanced probabilistic analysis, and robust design methodology. A three dimensional finite element model of a locking plate system with a supracondylar femoral fracture will be generated to investigate the device performance. The model will include all physiological loading conditions-hip contact, knee contact, and muscle forces-associated with a normal walking gait cycle. In conjunction with probabilistic methods, Taguchi design optimization will be used to optimize implant design to minimize the probability of failure.

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