The emergence of cyber physical frameworks has been catalyzed by various smart technologies including Next Generation Networks and 3D based Virtual Prototyping. Such frameworks hold the potential to support complex distributed collaborative practices in various engineering fields especially advanced manufacturing. This paper discusses the design and implementation of such a cyber physical framework based on Internet-of-Things (IoT) technologies while addressing semantic interoperability issues. The components of this framework is outlined along with an overview of the role of the emerging GENI based Next Internet technologies. The semantic framework is designed based on a Virtual Enterprise (VE) context where multiple organizations with similar as well as different capabilities can form temporary partnerships.

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