A microscale model of the brain was developed in order to understand the details of intracranial fluid cavitation and the damage mechanisms associated with cavitation bubble collapse due to blast-induced traumatic brain injury (TBI). Our macroscale model predicted cavitation in regions of high concentration of cerebrospinal fluid (CSF) and blood. The results from this macroscale simulation directed the development of the microscale model of the superior sagittal sinus (SSS) region. The microscale model includes layers of scalp, skull, dura, superior sagittal sinus, falx, arachnoid, subarachnoid spacing, pia, and gray matter. We conducted numerical simulations to understand the effects of a blast load applied to the scalp with the pressure wave propagating through the layers and eventually causing the cavitation bubbles to collapse. Collapse of these bubbles creates spikes in pressure and von Mises stress downstream from the bubble locations. We investigate the influence of cavitation bubble size, compressive wave amplitude, and internal bubble pressure. The results indicate that these factors may contribute to a greater downstream pressure and von Mises stress which could lead to significant tissue damage.
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ASME 2015 International Mechanical Engineering Congress and Exposition
November 13–19, 2015
Houston, Texas, USA
Conference Sponsors:
- ASME
ISBN:
978-0-7918-5738-0
PROCEEDINGS PAPER
Virtual Simulation of the Effects of Intracranial Fluid Cavitation in Blast-Induced Traumatic Brain Injury
Shivonne Haniff,
Shivonne Haniff
Sandia National Laboratories, Albuquerque, NM
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Paul Taylor,
Paul Taylor
Sandia National Laboratories, Albuquerque, NM
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Aaron Brundage,
Aaron Brundage
Sandia National Laboratories, Albuquerque, NM
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Damon Burnett,
Damon Burnett
Sandia National Laboratories, Albuquerque, NM
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Candice Cooper,
Candice Cooper
Sandia National Laboratories, Albuquerque, NM
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Arne Gullerud,
Arne Gullerud
Sandia National Laboratories, Albuquerque, NM
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Ryan Terpsma
Ryan Terpsma
Sandia National Laboratories, Albuquerque, NM
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Shivonne Haniff
Sandia National Laboratories, Albuquerque, NM
Paul Taylor
Sandia National Laboratories, Albuquerque, NM
Aaron Brundage
Sandia National Laboratories, Albuquerque, NM
Damon Burnett
Sandia National Laboratories, Albuquerque, NM
Candice Cooper
Sandia National Laboratories, Albuquerque, NM
Arne Gullerud
Sandia National Laboratories, Albuquerque, NM
Ryan Terpsma
Sandia National Laboratories, Albuquerque, NM
Paper No:
IMECE2015-52696, V003T03A062; 10 pages
Published Online:
March 7, 2016
Citation
Haniff, S, Taylor, P, Brundage, A, Burnett, D, Cooper, C, Gullerud, A, & Terpsma, R. "Virtual Simulation of the Effects of Intracranial Fluid Cavitation in Blast-Induced Traumatic Brain Injury." Proceedings of the ASME 2015 International Mechanical Engineering Congress and Exposition. Volume 3: Biomedical and Biotechnology Engineering. Houston, Texas, USA. November 13–19, 2015. V003T03A062. ASME. https://doi.org/10.1115/IMECE2015-52696
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