In recent years, magnesium alloys have emerged as possible biodegradable implant material. A fundamental understanding of the nature of magnesium corrosion and the ability to control this process in vivo is critical to advancing the case for clinical use of magnesium based biomaterials. The biodegradation of magnesium is fundamentally linked to studies of its corrosion, which is dependent on the interfacing dynamics between the material and its environment. Thus, it is required to confirm what variable differentiate the corrosion behavior between in vitro and in vivo before optimizing and standardizing of in vitro test. This study was conducted to understand the biodegradation behavior of commercial AZ31 and Mg-Zn-Ca alloys with plasma electrolyte oxidation (PEO) under various biological environments using in vivo and in vitro testing methods mimicking in vivo physiological environment. This study is focused on the effect of Zn element concentration and PEO coating for magnesium alloys, and the correlation between the in vivo and in vitro in terms of corrosion rate, types of corrosion and corrosion product formation.
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ASME 2014 International Mechanical Engineering Congress and Exposition
November 14–20, 2014
Montreal, Quebec, Canada
Conference Sponsors:
- ASME
ISBN:
978-0-7918-4963-7
PROCEEDINGS PAPER
Biodegradable Magnesium Implant: In Vivo and In Vitro Convergence
Yeoheung Yun,
Yeoheung Yun
North Carolina A&T State University, Greensboro, NC
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Yongseok Jang,
Yongseok Jang
North Carolina A&T State University, Greensboro, NC
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Juan Wang,
Juan Wang
North Carolina A&T State University, Greensboro, NC
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Zhongyun Dong,
Zhongyun Dong
University of Cincinati, Cincinnati, OH
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Vesselin Shanov,
Vesselin Shanov
University of Cincinati, Cincinnati, OH
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Jagannathan Sankar,
Jagannathan Sankar
North Carolina A&T State University, Greensboro, NC
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Youngmi Koo,
Youngmi Koo
North Carolina A&T State University, Greensboro, NC
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Leon White,
Leon White
North Carolina A&T State University, Greensboro, NC
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Boyce Collins
Boyce Collins
North Carolina A&T State University, Greensboro, NC
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Yeoheung Yun
North Carolina A&T State University, Greensboro, NC
Yongseok Jang
North Carolina A&T State University, Greensboro, NC
Juan Wang
North Carolina A&T State University, Greensboro, NC
Zhongyun Dong
University of Cincinati, Cincinnati, OH
Vesselin Shanov
University of Cincinati, Cincinnati, OH
Jagannathan Sankar
North Carolina A&T State University, Greensboro, NC
Youngmi Koo
North Carolina A&T State University, Greensboro, NC
Leon White
North Carolina A&T State University, Greensboro, NC
Boyce Collins
North Carolina A&T State University, Greensboro, NC
Paper No:
IMECE2014-39262, V014T11A014; 6 pages
Published Online:
March 13, 2015
Citation
Yun, Y, Jang, Y, Wang, J, Dong, Z, Shanov, V, Sankar, J, Koo, Y, White, L, & Collins, B. "Biodegradable Magnesium Implant: In Vivo and In Vitro Convergence." Proceedings of the ASME 2014 International Mechanical Engineering Congress and Exposition. Volume 14: Emerging Technologies; Engineering Management, Safety, Ethics, Society, and Education; Materials: Genetics to Structures. Montreal, Quebec, Canada. November 14–20, 2014. V014T11A014. ASME. https://doi.org/10.1115/IMECE2014-39262
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