We report on a microfluidic device capable of sorting nanoscale particulates and water-in-oil emulsions at high-throughput. The device is passive, relying solely on hydrodynamic forces and the emulsion mass to achieve separation. We use the microfluidic device to deliver surfactants and lipids to the emulsion surface. This is achieved by immersing the emulsions in a fluid stream with a high concentration of the nano-particulates. The particulates assemble on the surface of the emulsions as they are transported along the stream. The emulsions are then transferred (i.e. separated) into a second fluid stream that is devoid of surrounding material. The performance of the device is evaluated for a range of flow rates, nano-particulate concentrations, and emulsion sizes. We report separation efficiencies that exceed current technologies over a wide range of flow rates. The microfluidic device can be used to produce delivery vehicles for pharmaceuticals and models for membrane biology studies.
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ASME 2014 International Mechanical Engineering Congress and Exposition
November 14–20, 2014
Montreal, Quebec, Canada
Conference Sponsors:
- ASME
ISBN:
978-0-7918-4954-5
PROCEEDINGS PAPER
Particulate and Emulsion Sorting Using Microfluidics
Li Lu,
Li Lu
State University of New York at Binghamton, Binghamton, NY
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Rebecca M. Irwin,
Rebecca M. Irwin
State University of New York at Binghamton, Binghamton, NY
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Jeffrey W. Schertzer,
Jeffrey W. Schertzer
State University of New York at Binghamton, Binghamton, NY
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Paul R. Chiarot
Paul R. Chiarot
State University of New York at Binghamton, Binghamton, NY
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Li Lu
State University of New York at Binghamton, Binghamton, NY
Rebecca M. Irwin
State University of New York at Binghamton, Binghamton, NY
Jeffrey W. Schertzer
State University of New York at Binghamton, Binghamton, NY
Paul R. Chiarot
State University of New York at Binghamton, Binghamton, NY
Paper No:
IMECE2014-38298, V007T09A065; 4 pages
Published Online:
March 13, 2015
Citation
Lu, L, Irwin, RM, Schertzer, JW, & Chiarot, PR. "Particulate and Emulsion Sorting Using Microfluidics." Proceedings of the ASME 2014 International Mechanical Engineering Congress and Exposition. Volume 7: Fluids Engineering Systems and Technologies. Montreal, Quebec, Canada. November 14–20, 2014. V007T09A065. ASME. https://doi.org/10.1115/IMECE2014-38298
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