Concentration is a vital measure to collect samples in biology. The same measure can also benefit bio-signal enhancement. Conventionally, signal detection heavily relies on the sensitivity of sensors. However, background noise usually interferes with the accuracy as the sample concentration level is below a threshold. The signals are even weaker especially in miniaturized diagnostics or point-of-care devices. Alternatively, single cell/molecule detection was developed to break the engineering limitation and achieve better detectability. However, challenge concerning to single cell/molecule capturing and manipulation is a potential barrier in the field. In addition, the effectiveness of sampling remains an open quest under study. As a result, concentrating samples provides a simple, rapid, and direct means for enhancing weak bio-signal detection.
Dynamic Particle Concentration for Bio-Signal Enhancement Based on an Optoelectric Microchip
- Views Icon Views
- Share Icon Share
- Search Site
Wang, K, Wereley, ST, Kumar, A, & Chuang, H. "Dynamic Particle Concentration for Bio-Signal Enhancement Based on an Optoelectric Microchip." Proceedings of the ASME 2013 International Mechanical Engineering Congress and Exposition. Volume 7B: Fluids Engineering Systems and Technologies. San Diego, California, USA. November 15–21, 2013. V07BT08A001. ASME. https://doi.org/10.1115/IMECE2013-62329
Download citation file: