Regulatory engineering came to be increasingly needed by extensive people of our society to maintain safety, security, and sustainability of the environment, economy, energy, mineral and other resources of our planet among others, as engineering is increasingly globalized to meet the needs and wants of a variety of people and society in the world. The ASME/VUPRE Conference on Vulnerability, Uncertainty and Probability Quantification in Regulatory Engineering was to be held in Washington, D. C. on August 16–18, 2012 or thereafter. The current paper provides an overview of the planned conference presentations and discussion, based on the topics planned, and abstracts submitted among others, as well as those for IMECE2012 Session 5-7-2 Globalization of Regulatory Engineering, and the author’s paper on fatigue and fracture issues of an offshore structure, etc., and role of regulatory engineering, prepared for the 9th International Conference on Fracture and Strength of Solids (FEOFS2013) on June 9–13, 2013 in Jeju, South Korea. Possible impacts of the outcome on the regulatory agencies, regulated communities, scientists and engineers, and general public in the United States, Europe and Japan among other nations and regions are also discussed.

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