Non-invasive diagnosis of cardiovascular diseases is a valuable tool to reduce patient’s risk and discomfort. The main aim of this work is to investigate the possibilities of using computational fluid dynamics as a tool to investigate the biomechanical characteristics of the aorta under different medical conditions. These conditions include an aorta with healthy conditions, atherosclerosis and aneurysm. A three dimensional pulsatile flow model for an elastic aorta is developed and constructed in ANSYS® CFX 12. Abnormalities are simulated as diameter changes at the root of the ascending aorta. The computational model shows the reflection of these diseases on the blood flow and the artery wall at other locations downstream along the aorta. This 3D model has several advantages over previously published 1D and 2D models by giving more realistic results as compared with clinical trials.

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