In this work we present test methods, devices, and preliminary results for the mechanical characterization of the small bowel for intraluminal mobility. Both active and passive forces that affect mobility are investigated. The active forces are generated by the migrating motor complex and the movement of muscular organs within and surrounding the peritoneal cavity. Passive forces develop from the biomechanical response of the tissue, the tribology of the mucosa, mucoadhesion, and the orientation and mass of surrounding tissue. Four investigative devices and testing methods to characterize the active and passive forces are presented in this work. These are: 1) A novel manometer and a force sensor array that measure forces generated by the migrating motor complex; 2) A biaxial test apparatus and method for characterizing the biomechanical properties of the duodenum, jejunum, and ileum; 3) A novel in vitro protocol and device designed to measure the force required to overcome mucoadhesion; 4) A novel tribometer that measures in vivo coefficient of friction between the mucus membrane and the robot surface.
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ASME 2010 International Mechanical Engineering Congress and Exposition
November 12–18, 2010
Vancouver, British Columbia, Canada
Conference Sponsors:
- ASME
ISBN:
978-0-7918-4426-7
PROCEEDINGS PAPER
Preliminary Mechanical Characterization of the Small Bowel for In Vivo Mobility
Benjamin S. Terry,
Benjamin S. Terry
University of Colorado, Boulder, CO
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Jonathan A. Schoen,
Jonathan A. Schoen
University of Colorado Hospital, Denver, CO
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Allison B. Lyle,
Allison B. Lyle
University of Colorado, Boulder, CO
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Mark E. Rentschler
Mark E. Rentschler
University of Colorado, Boulder, CO
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Benjamin S. Terry
University of Colorado, Boulder, CO
Jonathan A. Schoen
University of Colorado Hospital, Denver, CO
Allison B. Lyle
University of Colorado, Boulder, CO
Mark E. Rentschler
University of Colorado, Boulder, CO
Paper No:
IMECE2010-37010, pp. 305-314; 10 pages
Published Online:
April 30, 2012
Citation
Terry, BS, Schoen, JA, Lyle, AB, & Rentschler, ME. "Preliminary Mechanical Characterization of the Small Bowel for In Vivo Mobility." Proceedings of the ASME 2010 International Mechanical Engineering Congress and Exposition. Volume 2: Biomedical and Biotechnology Engineering. Vancouver, British Columbia, Canada. November 12–18, 2010. pp. 305-314. ASME. https://doi.org/10.1115/IMECE2010-37010
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