In every case where dissimilar materials are bonded together and undergo a subsequent change of dimension due to change of temperature, particle size and types, stresses develop at the interface due to mismatch of material properties. The magnitude of the stresses can be very large and may have a significant influence on the life of each material in the bonded construct. The potential application of nanocomposite cement in biomedical industry requires evaluating the material mismatch effects on the fracture toughness of bone-nanocomposite interfaces. Three point bend tests were conduct in this study on bovine femoral cortical bone and composite cements (Cobalt HV bone cement with 36 μm and 27 nm MgO additives) bonded specimen to measure the material mismatch effect on the interface fracture toughness. Experimental results found that particles size has significant influence on the interface fracture toughness of the bone-composite cements.

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