Drug delivery systems have had a profound impact on several branches of medicine. Engineers and researchers alike have labored to create a controlled drug delivery device capable of regulated dosage release and a specific cell targeting mechanism. The growing field of biomimicry has inspired several of these drug systems, though success has been limited. The flagellated low Reynolds number propulsion system of Salmonella typhimurium has inspired this specific delivery complex. In this system, the helical flagellar filaments of S. typhimurium are isolated from the bacteria’s cell body and are bound to functionalized paramagnetic microspheres. As a magnetic field is applied to this device, the microsphere rotates, inducing rotation of the helical flagella. This motion creates a locomotive force and drives the device in a predestined direction.
Biologically Inspired Robotic Microswimmers
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Hesse, WR, Federici, M, Casale, DM, Fink, P, Milton, B, & Kim, MJ. "Biologically Inspired Robotic Microswimmers." Proceedings of the ASME 2009 International Mechanical Engineering Congress and Exposition. Volume 12: Micro and Nano Systems, Parts A and B. Lake Buena Vista, Florida, USA. November 13–19, 2009. pp. 577-582. ASME. https://doi.org/10.1115/IMECE2009-10565
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