A device to measure and modulate individual cell temperatures in a tissue culture during cooling and freezing would enhance understanding of tissue freezing. Prefabrication experimentation and modeling were carried out to understand the behavior of the device. Modeling demonstrated that the thermocouples used in the system can be adequately isolated from each other to prevent interference in data collection. Experiments have shown that it is feasible to produce the thermocouples and thermoelectric heaters (TECs) required for fabrication of the device through electrodeposition.

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