2D and 3D multi-physics experiment-based nonlinear models with fluid-structure interactions (FSI) and structure-structure interactions (SSI) are introduced to model blood flow and stress/strain distributions in stenotic arteries with lipid pools. Material properties for the vessel and plaque are based on experimental measurements and information available in the literature (Huang et. al., 2001; Tang et. al., 2001). The Navier-Stokes equations are used as the governing equations for the fluid. Mooney-Rivlin models are used for both arteries and lipid cores. A well-tested finite element package ADINA is used to solve the models to perform flow and stress/strain analysis. Our results indicate that artery plaque stress/strain distributions are affected considerably (50%–400% or even more) by vessel material properties, stenosis severity and eccentricity, tube axial pre-stretch, pressure conditions, lipid core material property, size, position and geometry, and fluid-structure and structure-structure (vessel wall and lipid core) interactions. Differences in model assumptions and controlling factor specifications must be taken into consideration when interpreting the significance of computational results.
Quantifying Effects of Controlling Factors on Flow and Stress Distribution in Stenotic Arteries With Lipid Cores
- Views Icon Views
- Share Icon Share
- Search Site
Tang, D, Yang, C, Kobayashi, S, & Ku, DN. "Quantifying Effects of Controlling Factors on Flow and Stress Distribution in Stenotic Arteries With Lipid Cores." Proceedings of the ASME 2003 International Mechanical Engineering Congress and Exposition. Advances in Bioengineering. Washington, DC, USA. November 15–21, 2003. pp. 53-54. ASME. https://doi.org/10.1115/IMECE2003-41113
Download citation file: