Systems of Systems (SoS) are networks of systems that operate together synergistically. The response of these SoS to unexpected constituent system failures can undermine their effectiveness. One potential solution is to increase the SoS’s hard (physical design) or soft (human intervention) resilience. The costs and demands on humans increase greater than linearly as SoS scale increases. These limitations require a novel approach to improve SoS resilience. We hypothesize that Biologically Inspired (BID) network design can improve SoS resilience. A systems dynamics model of a Forestry Industry is presented and an optimization search over potential hard and soft resilience approaches is compared to a BID network improvement. SoS resilience is measured through the newly developed SoSRM. Results provide evidence that BID network design provides an approach to increase SoS resilience beyond hard and soft resilience improvements alone (SoSRM increased from .922 to .926). Secondly, this work provides evidence that incorporating detrital actors increases SoS resilience (SoSRM increased from .909 to .926). Third, this paper documents the first case study that uses the new SoSRM metric to justify a design decision. Finally, we provide a counter-example to the theory that increased sustainability always results in increased resilience.