Though Unmanned Aerial System (UAS) operators have started to push for general acceptance into the National Airspace System (NAS), there remain significant and necessary areas of research. Despite the ‘Unmanned’ moniker, human factors serve a vital role in safe and robust operation. Numerous reports have placed human errors as significant factors in recent UAS incidents, leading many researchers to investigate a framework for analyzing these human factors that lead to incidents. In this paper, the use of Heart Rate Variability (HRV), as an indicator of operator pressure or cognitive load of a UAS operator, is considered. Furthermore, potential applications of HRV research are presented towards applying this new layer of human feedback information to adjust UAS operations to achieve a safer and more resilient UAS. This paper serves as an initial proposal for this bigger closed-loop thinking in UAS human factor research.

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