We present a custom built Biosensor Microassembly Platform (BMP) for assembling a nanoparticles-based microscale in-vivo biosensor. Conducting directed assembly of nanoparticles on a 0.01 mm2 microchip is a very challenging problem. Complexities arise from assembling micro-components of different materials, and assembling antibody functionalized nanoparticles into their predetermined nanoscale trenches on the biosensor. Using our designed platform, we merge vision information with motion control efficiently, so that precise manipulation of the stages and microscopes facilitates the assembly process of the in-vivo biosensor. Along with Biosensor Microassembly Platform system design and automation, we demonstrate assembly of an in-vivo biosensor which has numerous applications in biomedical and health industry.

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