It has been known that the initialization of fractional operators requires time-varying functions, a complicating factor. This paper simplifies the process of initialization of fractional differential equations by deriving Laplace transforms for the initialized fractional integral and derivative that generalize those for the integer-order operators. A companion paper in this conference determines the Laplace transforms for initialized fractional integrals of any order and fractional derivatives of order less than one. This paper extends the theory for the Laplace transform of the derivative to higher order and provides applications.

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