Optical traps have been used in a multitude of applications in biology, such as stretching DNA molecules and bacterial tails, due to their ability to study molecules in solution. In addition to being capable of applying and sensing forces, optical traps also have the ability to accurately apply and sense torques. Birefringent particles experience a torque when trapped in elliptically polarized light which has resulted in rotation rates over 400 Hz. By measuring the frequency content of the exiting beam, the rotation rates can be tracked and controlled. Here we describe an optical trap with feedback torque control that maintains rotational rates in the presence of increasing drag. As a result, this research has the potential to advance the understanding of rotary motor proteins such as F1ATPase.
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ASME 2007 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference
September 4–7, 2007
Las Vegas, Nevada, USA
Conference Sponsors:
- Design Engineering Division and Computers and Information in Engineering Division
ISBN:
0-7918-4804-3
PROCEEDINGS PAPER
Rotational Control of Birefringent Particles Using an Optical Trap
Daniel G. Cole,
Daniel G. Cole
University of Pittsburgh, Pittsburgh, PA
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Robert L. Clark
Robert L. Clark
Duke University, Durham, NC
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Kurt D. Wulff
Duke University, Durham, NC
Daniel G. Cole
University of Pittsburgh, Pittsburgh, PA
Robert L. Clark
Duke University, Durham, NC
Paper No:
DETC2007-35334, pp. 785-791; 7 pages
Published Online:
May 20, 2009
Citation
Wulff, KD, Cole, DG, & Clark, RL. "Rotational Control of Birefringent Particles Using an Optical Trap." Proceedings of the ASME 2007 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. Volume 3: 19th International Conference on Design Theory and Methodology; 1st International Conference on Micro- and Nanosystems; and 9th International Conference on Advanced Vehicle Tire Technologies, Parts A and B. Las Vegas, Nevada, USA. September 4–7, 2007. pp. 785-791. ASME. https://doi.org/10.1115/DETC2007-35334
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