Vibratory load transmission reduction for precision space optics is demonstrated through a new concept of electronic differential controlled isolation. Lightweight, compact and with very low power consumption, differential controlled isolation can meet the active/passive isolation performance needs in large precision optics, launch system, science instrument modules and observation systems. This includes large optic, interferometric and formation flying platforms. Inexpensive to manufacture, the technology provides flexibility in design to meet many challenges. Although the main thrust of this research was to address OTA truss/ISIM isolation needs, the developed technology is directly applicable to many mission critical needs in launch and deployment of precision space systems.