Abstract
By integrating operating experience, accident analysis, risk assessment and defense-in-depth philosophy into decision-making consideration, risk-informed regulation better focuses regulatory attention to an issue consistent with its risk significance, which facilitates the establishment of appropriate regulation without damaging nuclear safety at the same time. By referring to the inspection findings from nuclear power plant, this paper utilizes Mitigating System Performance Indicator (MSPI) and Significance Determination Process (SDP) for research. From perspectives of basic theory, risk analysis and regulatory application consideration, this paper analyzes the correlation and differences between MSPI and SDP. The work could provide reference for the application and promotion of Risk-informed Regulation Approaches.