With the development of digital instrument and control technology for nuclear power plants in recent decades, communication networks have become an important part of safety digital control systems, which takes charge in data exchange between the various sub-systems, and extremely impact on the reliability and safety of the entire I&C system. Traditional communication systems where some special features, such as reliability, safety, real-time, certainty, and independence are not strictly required are various illustrated. However, how to implement a communication system in a safety I&C system is rarely stated in current research. In this research, a reliable safety communication system applied in nuclear power plants is designed and analyzed. The five key characteristics of nuclear safety communication networks are explained, followed by explanation of how to achieve these characteristics. The analysis and verification of the designed system are also stated in this paper, which contributes to proving that the designed nuclear safety communication system could applied in the nuclear power plants.