Minor actinides in the spent fuel have strong radiotoxicity and very long half-life, the the properly dispose of spent fuel is indispensible to the development of nucler energy. Generally,we dispose the spent fuel by geological burying. But it can not compeletly solve the problem. Neutron transmutation is the only way to shorten the half-life of radioactive nuclides, under the irradiation of neutron MA nuclide will capture neutron or fission, and translate into the short lived nuclide or something valued nuclide. Reactivity temperature coefficient is an improtant safety parameter in nuclear reactor physics.In the reactor design, for the safely operation of reactor, reactivity temperature coefficient must be be negative. The introduction of MA in the PWR must have interference to the temperature coefficient. This paper mainly studied the influence of PWR transmutation minor actinide on the temperature coefficient.

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