Thermal Hydraulics (T-H) process exerts important effect on nuclear reactor systems. Due to their complexity, it is necessary to propose an appropriate approach for modeling and investigating the processes, such as multiscale modeling technique. The current work attempts to provide a scheme of conceptual multiscale entropy production approach in view of descriptions of thermal hydraulic characteristics in nuclear reactor system at local, component and system scales. Based on some fundamental principles, the optimal thermal hydraulics design (OTHD) procedure in implementing the approach is established. Moreover, two instances are considered to show the applicability of the current approach, with respect to local and system scale. In addition, the approach proposed would contribute to make deeper understanding of the thermal hydraulic processes.

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