This paper presents a new approach for fuel burn up evaluation and radioactive inventory calculation used in Tehran Research Reactor. The approach is essentially based upon the utilization of a program written by C# which integrates the cell and core calculation codes, i.e., WIMSD-4 and CITVAP, respectively. Calculation of fuel burn up and radioactive inventories has been done for 26 core configuration of Tehran Research Reactor with HEU fuel element. The present inventory and fuel enrichment of each fuel element have been calculated.

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