Results of calculation studies of the first stage of self-sufficient thorium cycle for CANDU reactor are presented in the paper. The first stage is preliminary accumulation of 233U in the CANDU reactor itself. Parameters of active core and scheme of fuel reloading were accepted the same as those for CANDU reactor. It was assumed for calculations, that enriched 235U or plutonium was used as additional fissile material to provide neutrons for 233U production. Parameters of 10 different variants of the elementary cell of active core were calculated for the lattice pitch, geometry of fuel channels, and fuel assembly of the CANDU reactor. The results presented in the paper allow to determine the time of accumulation of the required amount of 233U and corresponding number of targets going into processing for 233U extraction. Optimum ratio of the accumulation time to number of processed targets can be determined using the cost of electric power produced by the reactor and cost of targets along with their processing.

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