Formation of unwanted bubbles is one the main issues in biomicrofluidics-based applications such as lab-on-a-chip devices, and adversely affects the performance of these systems. In this work we report a simple and efficient method for removing gas bubbles from liquid filled microchannels. This bubble removal system consists of a cavity on which a hydrophobic membrane is bonded parallel to the main fluidic channel to vent gas bubbles normal to the flow direction. A T-junction configuration is used to generate gas bubbles prior to entering the bubble removal cavity. A finite volume-based computational model is developed using ANSYS FLUENT to simulate gas removal characteristics of the system. The effects of various geometric parameters and operating conditions are studied both through numerical simulations and experimentally.
- Heat Transfer Division
- Fluids Engineering Division
Computational and Experimental Study of Gas Bubbles Removal in a Microfluidic System
Derami, HG, & Darabi, J. "Computational and Experimental Study of Gas Bubbles Removal in a Microfluidic System." Proceedings of the ASME 2015 13th International Conference on Nanochannels, Microchannels, and Minichannels collocated with the ASME 2015 International Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Microsystems. ASME 2015 13th International Conference on Nanochannels, Microchannels, and Minichannels. San Francisco, California, USA. July 6–9, 2015. V001T04A066. ASME. https://doi.org/10.1115/ICNMM2015-48561
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