Dielectrophoresis (DEP) is a powerful tool for particle and cell manipulations in microfluidic devices. Our group has recently developed a new method that exploits the intrinsic curvature of microchannel walls for a diverse electrical control of particle and cell motions, which is termed Curvature-induced Dielectrophoresis (C-iDEP). Due to the variation in path length for electric current, the electric field becomes inherently non-uniform within a microchannel turn. Thus induced DEP can generate a cross-stream particle motion, which is a nonlinear function of electric field and superimposed to the linear electrokinetic motion enabling flexible particle manipulations. This paper presents our recent results on the deflection, focusing, filtration, and separation of particles and cells in curved microchannels by the use of C-iDEP.
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ASME 2012 10th International Conference on Nanochannels, Microchannels, and Minichannels collocated with the ASME 2012 Heat Transfer Summer Conference and the ASME 2012 Fluids Engineering Division Summer Meeting
July 8–12, 2012
Rio Grande, Puerto Rico, USA
Conference Sponsors:
- Heat Transfer Division
- Fluids Engineering Division
ISBN:
978-0-7918-4479-3
PROCEEDINGS PAPER
Curvature-Induced Dielectrophoresis (C-iDEP) for Microfluidic Particle and Cell Manipulations
Xiangchun Xuan
Xiangchun Xuan
Clemson University, Clemson, SC
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Xiangchun Xuan
Clemson University, Clemson, SC
Paper No:
ICNMM2012-73042, pp. 681-685; 5 pages
Published Online:
July 22, 2013
Citation
Xuan, X. "Curvature-Induced Dielectrophoresis (C-iDEP) for Microfluidic Particle and Cell Manipulations." Proceedings of the ASME 2012 10th International Conference on Nanochannels, Microchannels, and Minichannels collocated with the ASME 2012 Heat Transfer Summer Conference and the ASME 2012 Fluids Engineering Division Summer Meeting. ASME 2012 10th International Conference on Nanochannels, Microchannels, and Minichannels. Rio Grande, Puerto Rico, USA. July 8–12, 2012. pp. 681-685. ASME. https://doi.org/10.1115/ICNMM2012-73042
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