In this article, microdroplet motion in the electrocapillary-based digital microfluidic systems is modeled accurately, and the combined effects of the biomolecular adsorption and micro-droplet evaporation on the performance of the device are investigated. An electrohydrodynamic approach is used to model the driving and resisting forces, and Fick’s law and Gibbs equation are used to calculate the microdroplet evaporation and adsorption rate. Effects of the adsorption and evaporation rates are then implemented into the microdroplet dynamics by adding new terms into the force balance equation. It is shown that mass loss due to the evaporation tends to increase the protein concentration, and on the other hand, the increased concentration due to the mass loss increases the biomolecular adsorption rate which has a reverse effect on the concentration. The modeling results indicate that evaporation and adsorption play crucial roles in the microdroplet dynamics.
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ASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels
June 19–22, 2011
Edmonton, Alberta, Canada
Conference Sponsors:
- Heat Transfer Division
ISBN:
978-0-7918-4463-2
PROCEEDINGS PAPER
Numerical Investigation of the Combined Effects of Biomolecular Adsorption and Microdroplet Evaporation on the Performance of the Electrocapillary-Based Digital Microfluidic Systems
Ali Ahmadi,
Ali Ahmadi
University of British Columbia, Kelowna, BC, Canada
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Mina Hoorfar
Mina Hoorfar
University of British Columbia, Kelowna, BC, Canada
Search for other works by this author on:
Ali Ahmadi
University of British Columbia, Kelowna, BC, Canada
Mina Hoorfar
University of British Columbia, Kelowna, BC, Canada
Paper No:
ICNMM2011-58166, pp. 139-147; 9 pages
Published Online:
May 11, 2012
Citation
Ahmadi, A, & Hoorfar, M. "Numerical Investigation of the Combined Effects of Biomolecular Adsorption and Microdroplet Evaporation on the Performance of the Electrocapillary-Based Digital Microfluidic Systems." Proceedings of the ASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels. ASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels, Volume 1. Edmonton, Alberta, Canada. June 19–22, 2011. pp. 139-147. ASME. https://doi.org/10.1115/ICNMM2011-58166
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