Surface Acoustic Wave-Induced Microstreaming in Droplets for the Enhancement of Biosensing Performances

A droplet-based micro-total analysis system (microTAS) based on digital microfluidics, involving surface acoustic wave (SAW) microstreaming dedicated to the enhancement of the performance of biosensors was designed and studied. We first present the characterization of the flow induced in the droplet during SAW stirring. We then present the evaluation of the biosensor performance enhancement obtained using SAW, evaluated by finite element simulation. We finally stress on the importance of the Damko¨her and Peclet numbers in the design of stirring-based microTAS systems.