Electroosmotic flow is widely used to transport and mix fluids in microfluidics. Aiming at the parallel-plate microchannel with sinusoidal surface roughness, this paper solved the governing equations using the finite element method and the effects of roughness height and frequency on mixing efficiency are investigated. The simulation results indicate that the mixing efficiency increases with the roughness height and frequency, which is approximately proportional to the roughness height. The results can provide valuable insights into the efficient mixing in microfluidics with rough surface and the optimal design of microchannel.

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