Within the field of lab-on-a-chip systems large efforts are devoted to the development of onchip tools for particle handling and mixing in viscosity-dominated liquid flows on the sub-mm scale. One technology involves ultrasound with frequencies in the MHz range, which leads to wavelengths of the order of 0.1–1 mm suitable for mm-sized microchambers. Due to the nonlinearity of the governing acoustofluidic equations, second-order effects will induce steady forces on fluids and suspended particles through the effects known as acoustic streaming and acoustic radiation force. We extend the basic perturbation approach for treating these effects in systems at resonance in various geometries. The first-order eigenmodes are used as source terms for the time-averaged viscous second-order equations. The theory is applied to explain experimental results on aqueous microbead solutions in silicon-glass microchips.
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ASME 2008 6th International Conference on Nanochannels, Microchannels, and Minichannels
June 23–25, 2008
Darmstadt, Germany
Conference Sponsors:
- Nanotechnology Institute
ISBN:
0-7918-4834-5
PROCEEDINGS PAPER
Acoustofluidic Simulations: Ultrasound Handling of Liquids and Particles in Microfluidic Systems
Peder Skafte-Pedersen,
Peder Skafte-Pedersen
Technical University of Denmark, Lyngby, Denmark
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Henrik Bruus
Henrik Bruus
Technical University of Denmark, Lyngby, Denmark
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Peder Skafte-Pedersen
Technical University of Denmark, Lyngby, Denmark
Henrik Bruus
Technical University of Denmark, Lyngby, Denmark
Paper No:
ICNMM2008-62057, pp. 1799-1805; 7 pages
Published Online:
June 11, 2009
Citation
Skafte-Pedersen, P, & Bruus, H. "Acoustofluidic Simulations: Ultrasound Handling of Liquids and Particles in Microfluidic Systems." Proceedings of the ASME 2008 6th International Conference on Nanochannels, Microchannels, and Minichannels. ASME 2008 6th International Conference on Nanochannels, Microchannels, and Minichannels. Darmstadt, Germany. June 23–25, 2008. pp. 1799-1805. ASME. https://doi.org/10.1115/ICNMM2008-62057
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