This work demonstrates a new mechanism for changing the architecture of microfluidic channels during device operation. This method uses an aqueous solution of a thermally responsive polymer (Pluronic), which undergoes reversible gel formation at elevated temperatures. This gelation temperature is lowered through the presence of sodium phosphate. A phase diagram for this material system is derived from rheometry experiments. Formation of a temporary gel wall in a microfluidic device occurs at the diffusive interface between a Pluronic solution and a sodium phosphate solution. The wall thickness increases along the channel, and it decreases at high flow rates. The wall thickness also increases with saline concentration. These observations are explained through scaling arguments for the diffusion problem and with the established phase diagram.
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ASME 2008 6th International Conference on Nanochannels, Microchannels, and Minichannels
June 23–25, 2008
Darmstadt, Germany
Conference Sponsors:
- Nanotechnology Institute
ISBN:
0-7918-4834-5
PROCEEDINGS PAPER
Formation of Temporary Separating Walls in Microfluidic Devices
Vahid Bazargan,
Vahid Bazargan
University of British Columbia, Vancouver, BC, Canada
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Boris Stoeber
Boris Stoeber
University of British Columbia, Vancouver, BC, Canada
Search for other works by this author on:
Vahid Bazargan
University of British Columbia, Vancouver, BC, Canada
Boris Stoeber
University of British Columbia, Vancouver, BC, Canada
Paper No:
ICNMM2008-62360, pp. 1245-1251; 7 pages
Published Online:
June 11, 2009
Citation
Bazargan, V, & Stoeber, B. "Formation of Temporary Separating Walls in Microfluidic Devices." Proceedings of the ASME 2008 6th International Conference on Nanochannels, Microchannels, and Minichannels. ASME 2008 6th International Conference on Nanochannels, Microchannels, and Minichannels. Darmstadt, Germany. June 23–25, 2008. pp. 1245-1251. ASME. https://doi.org/10.1115/ICNMM2008-62360
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